Prescription orlistat is used to help patients lose weight who are overweight (BMI over 30 or over 28 with specific health issues). Typically, a doctor’s advised combination of a nutritious diet and regular exercise is employed with it.

You can take 120 mg of orlistat tablets up to three times a day with a meal that contains fat. Results from the efficient weight-loss medication orlistat 120mg should be visible in two weeks.

You can use your account to message our experts for free assistance if you have any queries regarding orlistat, weight loss medications in general, or your health. This can be done either before or after you begin treatment.

Orlistat 120mg

In three to six months, orlistat, a weight-loss medication, can help you shed more than 10% of your body weight. Purchase diet pills online for quick, discrete delivery.

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About Orlistat

What is orlistat?

Overweight people who take prescription weight reduction pills can lose weight with the help of orlistat. It accomplishes this by stopping their ability to absorb and digest fat. It doesn’t decrease hunger or eliminate body fat.

Only patients with a BMI of over 30 or older who have specific medical conditions, such as type 2 diabetes or high blood pressure, are eligible to receive an orlistat prescription.

What type of drug is orlistat?

Orlistat is a member of the lipase inhibitor medication class. By altering the way your body absorbs fat, these medications cause your intestines to absorb a third less fat from food. When you use the restroom, this unabsorbed fat is transferred through your stool.

What is another name for orlistat?

Xenical and Alli are other brand names for the generic drug orlistat. These drugs are brand-name equivalents of orlistat. Every brand of orlistat functions exactly the same way.

What is orlistat used for?

People who struggle with obesity or unintended weight gain can benefit from using orlistat. For those who have attempted various weight loss methods but have not been successful, it may be a viable option.

How do you get approved for orlistat?

You will need to have an evaluation with a physician or weight loss specialist in order to receive an authorized prescription for orlistat.

Most of the time, doctors will only authorize weight reduction pills like orlistat after you have already tried to reduce your weight through exercise or diet modifications.

Only patients with a BMI of over 30 or older who have specific medical conditions, such as type 2 diabetes or high blood pressure, are eligible to receive an orlistat prescription.

How does orlistat work?

Orlistat functions by altering the way your body breaks down fat. When taken orally, it inhibits the intestinal enzyme lipase, which aids in the breakdown and digestion of fats. When lipase is inhibited, fat is not absorbed by your body; rather, it is eliminated as waste.

What does orlistat do to your body?

The lipase inhibitor orlistat is the active component in orlistat pills. This medicine stops particular lipase enzymes from dissolving dietary fats in your food. This causes some of the fat in your diet to pass through your stool when you go to the bathroom rather than being absorbed by your body.

How long does orlistat take to work?

It takes 1-2 days for orlistat to start working, but it can take up to 2 weeks before you notice any changes. Most people claim that the first three months of orlistat use are when they observe the greatest benefits.

How effective is orlistat?

One useful medicine for weight loss is orlistat. After taking it for three to six months, obese individuals can drop more than 10% of their body weight.

How much weight can you lose with orlistat in a month?

When you initially start taking orlistat, you should lose 0.5 to 1 kg every week, or around 2 to 4 kg in the first month. Individual differences exist in terms of outcomes, such as beginning weight and preexisting medical issues.

According to studies, orlistat users who exercised and followed a diet dropped about 8.5 kg in a year. During the same time frame, those who did not take orlistat dropped about 3 kg less than those who did.

Orlistat has been shown in certain trials to help people lose more than 10% of their body weight in three to six months.

Is orlistat safe for weight loss?

“Orlistat is safe for use in weight loss, yes. For more than a decade, this drug has been used to manage weight reduction. Long-term studies have demonstrated that there aren’t many adverse drug reactions that are commonly documented; the most frequent ones include loose stools, minor abdominal pain, and an increased desire to use the restroom. 

How to take orlistat

Orlistat capsules should be taken whole and swallowed with water. Take orlistat with meals that contain fat up to three times a day, or up to one hour after.

Please take note: Do not take a dose if you are not eating or if you are not eating anything fattening.

When to take orlistat

Right after a high-fat meal, or up to an hour later, is the ideal time to take orlistat. You don’t need to take orlistat if you eat a low-fat meal or none at all.

How long can you take orlistat for?

There is no time restriction on the amount of time you can safely take orlistat; nevertheless, it is usually used for three to six months. It is not advisable for you to keep taking orlistat capsules without first consulting your physician.

What happens if you take orlistat without eating?

There are no benefits to weight loss if you take orlistat without eating. The way orlistat works is by lowering the quantity of fat your body takes in from meals. There won’t be any reduction in fat intake if you quit eating, thus nothing will happen. For this reason, if you eat a low-fat meal, you also don’t need to take orlistat.

How to get the best results from orlistat

When used in conjunction with other weight loss strategies like a balanced diet and consistent exercise, orlistat is most successful. You can get advice from your dietitian or doctor.

What to eat when taking orlistat

Take orlistat pills with meals that are low in calories and fat and high in nutrients for the best effects. It is advised that you adhere to a diet that restricts your intake of fat to 30% of your total caloric intake while using orlistat.

Some easy ways you can reduce your fat intake include:

  • Eating leaner cuts of meat, such as turkey and chicken.
  • Switching to a diet higher in fruits and vegetables.
  • Trimming visible fat off your meat, and removing chicken skin.
  • Choosing low-fat options where possible, such as skimmed milk, low-fat spreads, and reduced-fat cheese.
  • Avoiding adding extra oil or butter when cooking. Choose cooking methods such as poaching, baking, and grilling.
  • Switching to spray oil, which can help you use less oil while cooking.
  • Avoiding snacking between meals.

What should you not eat while taking orlistat?

When using orlistat, you should stay away from foods that are heavy in fat. This is due to the fact that orlistat reduces the amount of fat your body is able to absorb, which causes the fat to pass through your stools.

Consuming foods high in fat can have the following negative consequences for you:

  • oily or fatty stools
  • oily spotting or discharge from rectum
  • stomach pain
  • increased flatulence
  • needing to go to the toilet more often and/or more urgently
  • loose bowel movements

Available orlistat dosages

Orlistat is available in 60mg and 120mg dosages

In the US OR UK, orlistat 60mg is sold both online and over the counter under the brand name Alli. Due to its decreased dosage, this orlistat-containing drug is marginally less effective for weight loss. Up to three times a day, orlistat 60 mg is taken with each meal for a daily total of 180 mg of orlistat.

The drug orlistat 120mg is available exclusively with a prescription and is also marketed under the name Xenical. Three times a day, orlistat 120 mg is taken with each meal, for a daily total of 360 mg of orlistat.

What is the difference between orlistat 60 and 120?

The dosage is what distinguishes orlistat 60 from 120. If not, the medications are same.

Although orlistat 120 has a larger risk of adverse effects than orlistat 60, it is also more effective. Because a doctor must ensure that the drug is safe and acceptable for you to take, it is only available with a prescription.

For the majority of people, orlistat 60 has been determined to be safe and effective in helping them lose weight. This is why it is sold without a prescription under the Alli brand.

Where can I buy orlistat 120mg in the US or UK?

Orlistat 120mg is only available with a prescription. With an appointment, you can obtain a prescription from your neighbourhood doctor, or you can safely and conveniently request orlistat therapy online from services like Pain Relief Centre Online Doctor.

Where to buy orlistat online?

Reputable online retailers like Pain Relief Centre Online Doctor sell orlistat. Prior to starting orlistat, you will need to answer a brief online health questionnaire in order to ensure that it is safe and appropriate for you to take it.

Please take note: Buying orlistat from reputable, regulated websites is both safe and allowed. Make sure the website is registered with the General Pharmaceutical Council (GPhC), the Medicines and Healthcare Products Regulatory Agency (MHRA), and the Care Quality Commission (CQC) before buying prescription drugs online, such as Orlistat. This indicates that actual doctors are running the website and giving out authentic prescription drugs.

What are the benefits of orlistat?

Orlistat tablets help people lose weight, reduce their BMI, and lower their cholesterol. This occurs as a result of your body excreting more fat from meals that it was previously absorbing.

According to certain research, orlistat can help people with diabetes manage their blood sugar levels and is also advantageous for high blood pressure.

Taking orlistat and not losing weight

“Orlistat often begins to work right away, and during the first few weeks, the majority of users lose weight. The results, though, might not appear for up to three months. It’s possible that orlistat is not the right medication for you if you’ve been taking it in addition to other weight-loss techniques for more than three months and haven’t lost weight. 

There are other medications besides orlistat that can be used to manage weight loss. Alternative weight loss methods might be a better fit for you if orlistat isn’t effective for you. Our medical professionals are able to counsel you and direct you toward the most appropriate weight loss program.

Orlistat side effects

Like any drug, orlistat may cause adverse reactions. They vary from extremely frequent to uncommon:

Very common:

  • headaches
  • abdominal pain
  • flatulence
  • oily and/or liquid stools
  • low blood sugar levels
  • upper respiratory infections
  • the flu


  • rectal pain/discomfort
  • soft stools
  • incontinence
  • bloating
  • tiredness
  • urinary tract infections (UTIs)


  • lower respiratory infection
  • gallstones
  • infectious diarrhoea
  • irregular menstrual cycle
  • gum disease
  • anxiety
  • muscle pain
  • feeling sick


  • allergic reaction
  • skin rash
  • abnormal liver function
  • internal bleeding
  • backache
  • decreased appetite
  • inflammation of the vagina
  • itching
  • visible water retention
  • vomiting

It is quite usual to experience a few common side effects when taking any drug. But if any adverse effects start to worry you, visit your doctor.

Long term orlistat side effects

Orlistat has not been shown to have any long-term negative effects, and as long as it works, it can usually be taken without risk.

Can you drink alcohol on orlistat?

It is possible to consume alcohol and take orlistat together. Alcohol and orlistat do not mix, hence there is no risk of negative responses or side effects. But since alcohol contains a lot of calories, it might interfere with your weight loss efforts.

Who shouldn't take orlistat?

It is important to discuss any pre-existing illnesses with your doctor when you see them about orlistat, along with any medications you are currently on. This is due to the fact that orlistat has a history of major drug interactions with various illnesses and medications.

Drug interactions with orlistat

It is well known that several medications can interact negatively with orlistat. Orlistat won’t be appropriate for you if you take any of the following:

  • blood thinners, like Warfarin
  • HIV medication
  • medication to treat fits (seizures)

Before taking orlistat, make sure to consult your doctor if you are already on any medications or have a medical condition that is not on this list.

Pre-existing conditions

The following conditions make it unsuitable for you to take orlistat:

  • digestive problems
  • gallbladder problems
  • underactive thyroid
  • kidney stones
  • eating disorders, like anorexia nervosa or bulimia
  • fits (seizures)
  • HIV

What diet pills are similar to orlistat?

Alternatives to orlistat include various orlistat-containing weight-loss medications and Mysimba, which contains the active components bupropion and naltrexone. Additionally, patients can administer injections to themselves.

Orlistat vs Xenical

A branded form of orlistat 120mg is called Xenical. This indicates that, despite the name on the box being different, the medication is exactly the same. Since Orlistat is a generic drug, any pharmaceutical company can make it, whereas only Roche can make Xenical. In general, generic drugs are less expensive and equally effective as branded ones.

Orlistat vs Alli

A marketed form of orlistat 60mg is called Alli. If you’re on Xenical, which is usually recommended at a dose of 120 mg, Alli is a lower-dose option.

The mechanisms of action and therapeutic efficacy of Alli and orlistat 60mg for weight loss are the same. The availability of Alli over-the-counter in the US is the only distinction between them but it can easily be gotten online from our.

Other medical weight loss treatment and options

Weight loss injections

Injection weight loss medications such as Saxenda and Wegovy are efficient weight loss therapies that function in a distinct manner from orlistat. Injections for weight loss function by suppressing your appetite, which enables you to consume fewer calories by eating less. Injectable weight-loss medications like Saxenda and Wegovy could be a suitable option if orlistat isn’t the right fit for you.


Unlike orlistat, the weight-loss pill Mysimba functions differently. Mysimba functions similarly to weight reduction injections in that it decreases appetite, making you feel fuller after consuming less food. Mysimba might be the best option for you if orlistat isn’t working as a medication and you find getting an injection every day painful.

Orlistat reviews

Patient reviews for orlistat indicate that it is rated:

Conclusion: Is orlistat good for weight loss?

Indeed, orlistat is a viable choice for people attempting to reduce their weight. It is a very effective medicine that doesn’t have any commonly documented major side effects and can help you lose more than 10% of your body weight in three to six months.

In addition, orlistat is less expensive than many other weight-loss medications and complements other weight-loss tactics like exercise and diets nicely.

Frequently asked questions

Orlistat 120mgMedically reviewed by:
Dr Crystal Wyllie

In 2010, Crystal graduated from Barts and the London School of Medicine and Dentistry with a medical degree. After that, she completed her GP training in hospitals and offices in London. Her areas of interest are women’s health, sexual health, and reproduction.

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