Mysimba 8 mg/90 mg  diet pills are available only with a prescription. By curbing your appetite and making you feel fuller after eating less, they can aid in weight loss. This enables you to reduce your caloric intake without experiencing hunger and to stick to a diet and exercise schedule.

Every day, one Mysimba 8 mg/90 mg diet pill is taken, first thing in the morning. Over the course of four weeks, your Mysimba dosage will be raised in order to lower the possibility of adverse effects like nausea. After beginning treatment, you ought to witness Mysimba outcomes in a few weeks.

Regular exercise and a healthy diet combined with Mysimba 8 mg/90 mg pills will yield the finest results. Mysimba is available for purchase online from reputable online medical providers

Mysimba 8 mg/90 mg

Mysimba is a prescription-only weight loss medication.

Delivery options

Free Standard Shipping Free Delivery Estimate: 2–5 business days. It’s  necessary for you to be home in order to sign for your box. Orders are sent out Monday through Friday. Your order will be shipped the same day if it is accepted by 4 p.m. Orders placed after 4 p.m. will be handled the next business day and sent.

The following day, select and collect $15. The next business day, if your order is authorized by 4 p.m., you can pick it up from the post office of your choice. Orders accepted after 4 p.m. will be ready for pickup in 2 business days. To find out when your order has been delivered to the Post Office of your choice, please check the tracking information you have.To pick up your purchase, you must provide a picture ID that matches the name on the order. The post office will hold your package for a period of 14days

-Available for pickup on  Express Delivery for $15. Arrival date estimated at 2 days
Should your order be accepted before 4 p.m., it will be delivered the next business day. Orders accepted after 4 p.m. will be delivered within 2 business days. It’s not necessary for you to be home in order to sign for your box.

How it works

Weight loss pens

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Weight loss pens

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Our pharmacy ships out your medication or test equipment, and Royal Mail delivers it to you. Another option is to pick it up from your neighborhood post office.

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About Mysimba

What is Mysimba?

The appetite-suppressant Mysimba 8 mg/90 mg  is a prescription drug. If you are fat or overweight, you can use it to help you lose weight. By suppressing your appetite, Mysimba pills help you feel fuller after eating less, which encourages you to eat less. It accomplishes this by acting on the area of your brain that controls hunger.

When combined with a balanced diet and frequent exercise, Mysimba 8 mg/90 mg can assist you in losing weight in a secure and efficient manner. Mysimba pills are taken once or twice a day, based on your doctor’s recommendation. After four months (16 weeks), losing at least 5% of your body weight is a normal Mysimba outcome.

What is Mysimba used for?

The sole purpose of Mysimba tablets is to aid in weight loss. If you are overweight and finding it difficult to reduce your weight with food and exercise alone, you may be offered Mysimba weight loss tablets.

If you have another medical issue that is made worse by your weight or is more risky if you are overweight, your doctor can also suggest Mysimba 8 mg/90 mg diet tablets.

Using Mysimba pills instead of following a fad diet will help you lose weight healthily.

How does Mysimba 8 mg/90 mg work?

The active components of Mysimba pills are bupropion hydrochloride and naltrexone hydrochloride. These target the parts of your brain that control your appetite, energy levels, and food intake.

You can consume less calories without experiencing hunger when you take Mysimba. This facilitates the adoption of healthy lifestyle modifications, including cutting back on snacking, for safe and efficient weight loss.

How long does Mysimba take to work?

Mysimba 8 mg/90 mg tablets begin to act as soon as you take them, but it may take a few weeks for you to notice the full benefits of the prescription. This is because you will be gradually increasing your Mysimba dosage during the first few weeks, as it takes some time to build up in your system.

Approximately 5% of your initial weight should be lost after 4 months of using Mysimba. Your doctor might recommend a different weight reduction strategy if you don’t drop five percent of your initial weight. Maintaining a nutritious diet and engaging in regular exercise are equally crucial to achieving your weight loss objectives when using Mysimba.

How effective is Mysimba 8 mg/90 mg?

Mysimba 8 mg/90 mg  pills have been demonstrated to be useful in promoting weight loss when used in conjunction with physical activity and a balanced diet. According to this 2020 study, compared to taking a placebo, taking Mysimba diet tablets helped significantly more persons drop at least 5% of their starting weight.

Another study discovered that taking bupropion and naltrexone together resulted in weight loss that persisted for the full 56-week period.

What are the benefits of Mysimba?

The benefits of taking Mysimba 8 mg/90 mg tablets include:

  • losing weight and maintaining a healthy weight
  • a less frustrating weight loss experience, especially if you find it difficult to deal with hunger while reducing your calorie intake
  • feeling less hungry, which makes it easier to reduce snacking and decrease your appetite levels over time
  • reducing the risk of health conditions that are more likely if you’re overweight or obese, such as high blood pressure, heart disease, stroke, heart attack, and diabetes

Is Mysimba effective for weight loss?

Yes, Mysimba typically produces positive weight loss outcomes. According to Onakpoya et al. (2020), most users lose at least 5% of their starting body weight. Regular exercise (at least 150 minutes per week) and a balanced diet that stays away from high-fat and high-sugar foods and beverages will help you get better Mysimba outcomes.

Mysimba ingredients – bupropion-naltrexone

The two active components in each Mysimba pill are bupropion hydrochloride (90 mg) and naltrexone hydrochloride (8 mg). It has been discovered that the naltrexone/bupropion combo is an efficient weight loss medication.

Because naltrexone binds to opioid receptors, it decreases hunger and lessens food cravings. By binding to dopamine and norepinephrine receptors, bupropion has an antidepressant impact that also aids in hunger suppression.

How to take Mysimba

With a glass of water, swallow the entire Mysimba tablet. Never take less Mysimba than what your doctor has prescribed. Mysimba is typically taken once or twice day.

Who can take Mysimba?

Mysimba weight loss tablets may be suitable for you if:

  • you’re over 18
  • you have a BMI (body mass index) of 30 or above
  • you have a BMI of 27 to 30, and are at risk of developing diabetes or other conditions related to being overweight

When determining a course of treatment, our doctors will evaluate your BMI as well as the entirety of your medical history and may prescribe off-label medication.

Does Mysimba work immediately?

The moment you take Mysimba tablets, they will begin to function. Although you won’t experience weight reduction results right away, the active components should start to take effect in the first few days. It will take some time for them to build up in your system.

How long can you stay on Mysimba 8 mg/90 mg?

Mysimba is prescribed solely if a physician certifies that it is beneficial to you. Your doctor will keep an eye on you to make sure the Mysimba tablets are effective in aiding in your weight loss.

After four months, if you haven’t dropped five percent of your body weight, your doctor can advise you to stop using Mysimba and try an other weight-loss drug.

Can you just stop taking Mysimba?

Mysimba tablets have been observed to take roughly 4 months to take full effect, so you should attempt to wait at least that long before discontinuing them. Nevertheless, you must to cease immediately in case you encounter severe adverse effects. Refer to the “Mysimba side effects section” for additional details. See your doctor before stopping Mysimba if you are not experiencing any severe side effects.

Mysimba dosage: What strength is Mysimba?

One tablet per morning is often the first dosage for Mysimba. After taking Mysimba for four weeks, this is then progressively increased to two pills, twice a day (four tablets a day). Naltrexone hydrochloride (8 mg) and bupropion hydrochloride (90 mg) are the two ingredients in each pill.

Only if your doctor has prescribed the maximum number of Mysimba tablets for you to take each day may you take them. During your therapy, your doctor will explain to you how to take your medication and the appropriate dosages.

It is never appropriate to take two doses to make up for missed ones. Proceed with taking your prescription as usual, skipping the missing dose.

Where can I buy Mysimba tablets in the US?

The majority of pharmacies in the US allow you to pay to get a prescription for Mysimba filled. Mysimba is not typically provided by the NHS, so you will need to obtain a private prescription and cover the entire cost of your care.

Mysimba is also available for purchase online in the US from reputable, licensed online medical providers like Purchasing Mysimba requires a doctor’s clearance. This is to ensure that taking Mysimba pills is safe and appropriate for you.

Can I buy Mysimba over-the-counter?

No, as Mysimba is a prescription medication, you cannot get it over-the-counter. This is to ensure that, before you take it, a doctor verifies that it is safe and appropriate for you. Before writing a prescription for Mysimba pills, your doctor will examine your overall health, weight, and any other medications you may be on.

Mysimba side effects

Like many drugs, mysimba pills have potential negative effects. That’s why the dosage of Mysimba is gradually increased in order to reduce the possibility of unpleasant side effects like headaches and nausea.

Common Mysimba side effects include:

  • anxiety
  • constipation
  • dizziness
  • headaches
  • hot flushes
  • insomnia
  • nausea (feeling sick) or vomiting (being sick)
  • heart palpitations
  • tiredness
  • taste changes
  • tinnitus
  • changes in blood pressure
  • itching
  • rashes
  • sweating
  • hair loss

See your doctor if you experience any of these Mysimba side effects. Mysimba should not be stopped abruptly without first consulting your physician.

Uncommon Mysimba side effects include:

  • hypersensitivity
  • abnormal dreams, agitation and mood swings
  • balance disorders
  • amnesia
  • tremors
  • motion sickness
  • abdominal discomfort
  • indigestion
  • burping or belching
  • hepatic enzyme increase
  • gallbladder inflammation
  • changes to your kidney blood tests
  • erectile dysfunction (ED)
  • an increase in thirst and appetite
  • urticarial skin rash

Rare Mysimba side effects include:

  • jaw pain
  • dehydration
  • irregular periods
  • chest pain
  • fever
  • blood and lymphatic system disorders
  • hallucinations
  • loss of consciousness
  • lip swelling and toothache
  • seizures (fits)
  • bleeding from your back passage
  • hernias
  • abdominal pain
  • changes to how often you pass urine
  • vaginal dryness, bleeding, and changes to your periods

If you get any of these side effects after taking Mysimba, you should speak to a doctor urgently.

Stop taking your Mysimba tablets and see a doctor straight away if you get these side effects:

  • difficulty breathing
  • dizziness or loss of consciousness
  • an allergic rash
  • chest pain
  • seizures
  • hallucinations
  • severe upper abdominal pain
  • mouth or lip swelling

What to do if you get Mysimba side effects

As your body adjusts to the drug, the majority of Mysimba side effects should go away, but you should always notify your doctor if you do. In the event that you have severe, intolerable side effects or suspect an allergic reaction to Mysimba, you should immediately contact 999 or visit the hospital.

Most Mysimba side effects are manageable at home. For instance, consider eating fewer quantities, staying hydrated, and staying away from fatty, greasy foods if you feel ill or start throwing up while taking Mysimba. If Mysimba gives you a headache, you can also take painkillers in addition to Mysimba.

What are the risks of Mysimba?

As long as your doctor has cleared Mysimba for your therapy, it is generally safe. However, not everyone can use Mysimba safely, and if you already have a medical issue, it might not be the best choice for you (contraindication).

Mysimba contraindications

You should not take Mysimba 8 mg/90 mg tablets if you

  • are pregnant or trying to conceive
  • have a history of an eating disorder
  • suffer from severe liver or kidney disease
  • experience uncontrolled hypertension
  • have ever had a seizure
  • have a nervous system tumour
  • experience benzodiazepine or alcohol withdrawal
  • use opiates or certain other medications like some antidepressants
  • take concomitant treatment containing bupropion or naltrexone

Mysimba 8 mg/90 mg tablets may not be suitable for people who:

  • have a history of bipolar disorder
  • are taking certain antidepressants
  • have a history of depression

Is Mysimba dangerous?

If Mysimba is approved for you, it poses no threat; if it weren’t, it wouldn’t be sold in the UK. If used by someone who has not been prescribed medication, it could be dangerous because Mysimba may interact with other medical conditions.

Before prescribing a drug, your doctor will always check to make sure it is safe for you to use. If any Mysimba side effects bother you, you can also consult a doctor.

“When taking a drug for the first time, it’s normal to feel anxious. You might encounter some adverse effects, and you never know how you might react. Recall that a physician would only prescribe a course of therapy if they believed it to be in your best interests.can always get in touch with them if you have any questions concerning the security of your prescription. The clinical lead for service expansion is Dr. Babak Ashrafi.

Medication that interacts with Mysimba

Mysimba tablets may not be suitable for you if you take:

  • antidepressants
  • opioid analgesics like codeine, morphine, or tramadol
  • drugs metabolised by cytochrome P450 (CYP) enzymes
  • anti-epileptics
  • medication for HIV
  • antiplatelet medication
  • medication used to treat Parkinson’s disease

Always let your doctor know about any medication you are currently taking before starting Mysimba diet pills. This is to make sure Mysimba won’t interact with these.

Mysimba and alcohol

If you are a heavy drinker who has recently stopped or if you want to stop while taking Mysimba, you should not take it. This is due to the increased likelihood of experiencing severe adverse effects, including a seizure or mental illness. Additionally, Mysimba can lower your tolerance to alcohol.

It’s possible that your doctor would advise you to limit or stay away from alcohol while taking Mysimba. Talk to your doctor right now if you currently consume a lot of alcohol and you haven’t told them about it.

Mysimba alternatives

We provide a variety of weight reduction therapies at our pain relief centre in case you are unable to take Mysimba, find that it isn’t working for you, or simply want to know what other Mysimba alternative treatments are out there.

In order to help you decide which weight reduction medicine is best for you, we’ve examined a few more options below, including weight loss pills and weight loss injections.

Mysimba vs Saxenda

The comparison chart below might help you better understand each weight-loss medicine, especially if you are trying to decide between Saxenda and Mysimba.

Wegovy is an additional injection for weight loss that contains semaglutide instead of liraglutide. You can switch from taking Saxenda to Wegovy if you’re already taking Saxenda.

Active ingredient



Recommended dosage

2 tablets, twice a day


Common side effects

headache, nausea, vomiting, constipation

headache, nausea, vomiting, constipation





Effective at helping people lose more weight than diet and exercise alone

67.5% of people lost 5% or more of their initial body weight after 12 weeks


From $124 for 1 month’s supply (112 Mysimba tablets)

From $71.00 per pen

Requires a prescription?



What it’s approved for

Weight loss

Weight loss

Mysimba vs Orlistat

The comparison table below might help you better understand each weight loss medicine, especially if you are trying to decide between Mysimba and Orlistat. An unbranded tablet known as orlistat is also sold under the brand name Xenical.

Active ingredient



Recommended dosage

1 tablet, twice a day

1 tablet (120mg), up to 3 times a day

Common side effects

Headache, nausea, vomiting, and constipation

Headache, abdominal pain, flatulence, oily/fatty stools



Up to 3 times a day, only with meals containing fat


Effective at helping people lose more weight than diet and exercise alone

Can help people lose 50% more weight than through diet and exercise alone


From $124 for 1 month’s supply (112 Mysimba tablets)

From $30.99 for 2 weeks of capsules

Requires a prescription?



What it’s approved for

Weight loss

Weight loss

Mysimba vs Ozempic

If you’re having trouble deciding between Ozempic and Mysimba, the comparison table below can help you see each weight loss drug more clearly.

Active ingredient



Recommended dosage

1 tablet, twice a day

1 mg

Common side effects

Headache, nausea, vomiting, and constipation

Headache, nausea, vomiting, and constipation



Once a week


Effective at helping people lose more weight than diet and exercise alone

66.9% of people lost at least 5% of their initial body weight after 24 months


From $124 for 1 month’s supply (112 Mysimba tablets)

From $162.00 per pen

Does it require a prescription?



What it’s approved for

Weight loss

Treating and managing type 2 diabetes

Mysimba reviews

Examining patient evaluations can provide valuable insight into other people’s experiences with Mysimba treatment. Tablets from Mysimba are rated:

  • 5 stars on (albeit there aren’t many reviews right now)
  • 6.6 out of 10, based on more than 1,500 reviews, on

Conclusion: Is Mysimba a good pill for me?

It has been discovered that using Mysimba tablets to reduce weight can be successful, particularly when combined with a diet and exercise program. Trying Mysimba weight loss pills or consulting one of our specialists is the only way to find out for sure if they’re a good fit for you. Before authorizing treatment, we’ll make sure Mysimba is the best fit for you.

Frequently asked questions

Mysimba 8 mg/90 mg Medically reviewed by:
Dr Babak Ashrafi  Clinical Lead for Service Expansion

Babak completed his medical studies at King’s College London in 2003. During his stay there, he also earned a bachelor’s degree in physiology. After completing his training in general practice (GP), he worked as a partner at a sizable inner-city GP practice in East London for several years. In 2007, he passed the Royal College of GPs membership exam.

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